Antimicrobial activities of curcumin extracted from selected Zingiberaceae species as potential halal active pharmaceutical ingredient

Abu Bakar, Ainaa Eliah and Othman, Rashidi and Mohtar, Mastura and Mohd Latiff, Nur Hanie and Wan Sulaiman, Wan Syibrah Hanisah and Mohd Hatta, Farah Ayuni and Ramya, Razanah (2023) Antimicrobial activities of curcumin extracted from selected Zingiberaceae species as potential halal active pharmaceutical ingredient. Journal of Halal Science and Technology, 2 (1). pp. 83-93. ISSN 2957-4188 E-ISSN 2957-4196

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Abstract

The ginger family (Zingiberaceae) includes plants with a distinct smell and taste that are commonly used as spices in the kitchen, but also in a variety of industries (pharmaceutical, medical, and cosmetic) due to their demonstrated biological activity. This study describes the antibacterial activity of curcumin extracts from selected species of the Zingiberaceae family namely “temu emas” (Curcuma zeodoria). “temu kunci” (Curcuma manga), “temu pauh” (Curcuma amada), “lempoyang” (Zingiber zerumbit) and “cekur” (Kaempferia galangal). Extracts of these compounds were studied on Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 35218), Salmonella typhimurium (ATCC 14028), Candida albicans (ATCC 10231) and Aspergilus brasiliensis (ATCC 16404). Turbidity is taken as an indication of growth, thus the lowest concentration, which remains clear after macroscopic evaluation is taken as the minimum inhibitory concentration (MIC). In conclusion, amongst the studied members of Zingiberaceae, temu emas curcumin natural pigment extracts showed the best antibacterial activities against E. coli ATCC 35218 (2 μg / μL), S. typhimurium ATCC 14028 (2 μg / μL), C. albicans ATCC 10231 (2 μg / μL), A. brasiliensis ATCC 16404 (2 μg / μL) and S. aureus ATCC 25923 (3 μg / μL). The outcome of this research will be contributing towards new natural carotenoid pigment sources as potential active pharmaceutical ingredients which can be beneficial to halal health-promoting products industry.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Zingiberaceae, Curcumin, Antimicrobial activity, Halal ingredient, Natural Pigment
Subjects:	BPC Science and Technology in Islam BPH Islamic Economics > BPH114.3 Halal industry science BPH Islamic Economics > BPH117.3 Halal Pharmaceutical R Medicine > RS Pharmacy and materia medica S Agriculture > S Agriculture (General) T Technology > TP Chemical technology > TP248.13 Biotechnology T Technology > TP Chemical technology > TP372.6 Halal food industry T Technology > TP Chemical technology > TP934 Paints, pigments, varnishes, etc
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	International Institute for Halal Research and Training (INHART) Kulliyyah of Architecture and Environmental Design Kulliyyah of Architecture and Environmental Design > Department of Landscape Architecture
Depositing User:	Dr rashidi othman
Date Deposited:	21 Jul 2023 10:09
Last Modified:	21 Jul 2023 10:09
URI:	http://irep.iium.edu.my/id/eprint/105650

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