Computational analysis of hemodynamic parameters in coronary arteries: effects of stenosis and bifurcation angle

Maowa, S.H and M. Masum Billah, Masum and K. E. Hoque, Ekram and Ifraj, N.F. and M. S. Hossain, Hossain and Hoq, S.M Afzal (2025) Computational analysis of hemodynamic parameters in coronary arteries: effects of stenosis and bifurcation angle. Journal of Mechanical Engineering and Sciences, 19 (4). 10908 -10922. ISSN 2289-4659 E-ISSN 2231-8380

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Abstract

Cardiovascular diseases (CVDs) are still becoming the number one cause of death around the world. Coronary artery disease (CAD) is one of the most prevalent types. It is exceedingly crucial to monitor hemodynamic parameters early and precisely in order to determine progresses to become more severe, particularly in regions where arteries bifurcated. This study employs computational fluid dynamics (CFD) simulations to investigate how stenosis and bifurcation angle influence blood flow in the coronary arteries. Seven idealized 3D models of coronary arteries have been developed to show various degrees of narrowing in the arteries. The Carreau model was used to model blood as a non-Newtonian fluid, and the Navier-Stokes equations were used to perform simulations across the cardiac cycle. Key hemodynamic variables like velocity, pressure, and wall shear stress (WSS) were extracted. Results demonstrate that areas with 85% stenosis had maximum velocity of 3.52 m/s, wall shear stress of 78 Pa, and pressures of up to 230 mmHg at time t = 0.63 s. These are high-risk areas for disease progression. These outcomes assist in understanding how the shape of arteries affects abnormal flow dynamics, which could help medical professionals find and treat CAD early on.

Item Type:	Article (Journal)
Uncontrolled Keywords:	CVDs, Coronary artery bifurcation, CFD, Stenosis, Hemodynamic parameters
Subjects:	T Technology > T Technology (General) T Technology > T Technology (General) > T11.95 Industrial directories
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering > Department of Science
Depositing User:	Dr. S M Afzal Hoq
Date Deposited:	07 Aug 2026 17:07
Last Update:	07 Aug 2026 17:07
Queue Number:	2026-08-Q4529
URI:	http://irep.iium.edu.my/id/eprint/130520

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