Subcutaneous panniculitis-like T-cell lymphoma: a case report of a solved conundrum

Jamali, Nabilah Rashida and Chi Adam, Khairul Bariah and Burhanudin, Nor Aszlitah and Harun, Nor Adilah and Hamdan, Asmah Hanim (2024) Subcutaneous panniculitis-like T-cell lymphoma: a case report of a solved conundrum. IIUM Medical Journal Malaysia, 23 (1). pp. 117-120. ISSN 1823-4631 E-ISSN 2735-2285

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Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare primary cutaneous lymphoma which often be very complexed to be diagnosed. Here we reported a case of a 38-year-old lady with wax and wane course of left facial swelling associated with prolonged pyrexia of unknown origin, lethargy and prominent weight loss. Multiple investigations were conducted to reach to the conclusive diagnosis. Histopathological showed infiltration of neoplastic lymphoid cells within the adipocyte clusters with hyperchromatic nuclei, small nucleoli and scant cytoplasm. Immunohistochemical analysis were immunoreactive to CD3, CD8 & TIA and negative to CD20, CD4 & CD56. Based on clinical findings, histopathology report and immunohistochemical analysis, the patient diagnosed with SPTCL. Hence, any suspicious maxillofacial swelling without obvious sign of infection and trauma shall be investigated until a final diagnosis is reached.

Item Type:	Article (Journal)
Additional Information:	5817/106701
Uncontrolled Keywords:	Lymphoma, facial, swelling, subcutaneous, panniculitis
Subjects:	R Medicine > RB Pathology R Medicine > RK Dentistry R Medicine > RL Dermatology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Oral Maxillofacial Surgery and Oral Diagnosis Kulliyyah of Medicine Kulliyyah of Medicine > Department of Pathology & Lab Medicine
Depositing User:	dr khairul bariah
Date Deposited:	13 Dec 2023 14:57
Last Modified:	14 Aug 2024 12:11
URI:	http://irep.iium.edu.my/id/eprint/106701

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