Evaluation of adverse effects of sodium stibogluconate in the treatment of visceral leishmaniasis

Miah, Md Abdus Sattar and Salam, Md. Abdus and Haque, Md Azizul and Azad, Md. Azizul Haqur and Haque, Md. A.K.M. Enamul and Islam, Quazi Tarikul and Ekram, A.R.M.Saifuddin (2012) Evaluation of adverse effects of sodium stibogluconate in the treatment of visceral leishmaniasis. KYAMC Journal, 3 (1). pp. 239-243. ISSN 2308-2720

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Abstract

This descriptive cross-sectional study was carried out in the Department of Medicine, Rajshahi Medical College Hospital to evaluate the adverse effects of sodium stibogluconate in the treatment of visceral leishmaniasis. Out of 30 patients, 19 patients (63.33%) developed abnormalities in ECG. Among them 14 patients (46.67%) developed prolonged QTc, 6 patients (20%) developed Twave inversion and 1 patient (3.33%) developed transient first degree heart block. No patient developed symptomatic arrhythmia. Five patients (16.67%) developed transient raise of bilirubin, 11 patients (36.67%) developed raised SGPT. None of them developed clinical hepatitis. Twenty three patients (76.67%) developed raised serum amylase but none developed clinical pancreatitis. There was no change in renal function. No adverse effects were noted on complete blood count.

Item Type:	Article (Journal)
Additional Information:	9217/87307
Subjects:	R Medicine > RC Internal medicine > RC111 Infectious and Parasitic Diseases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical
Depositing User:	Prof. Dr. Md. Abdus Salam
Date Deposited:	07 Jan 2021 12:29
Last Modified:	28 Jan 2021 09:00
URI:	http://irep.iium.edu.my/id/eprint/87307

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