Asymptomatic primary biliary cholangitis in a young patient: an incidental finding

Kamarudin, Norhidayah and Chuan, Hun Ding and Md Isa, Nurismah and Md Pauzi, Suria Hayati and Abdul Wahab, Asrul (2020) Asymptomatic primary biliary cholangitis in a young patient: an incidental finding. Gazi Medical Journal, 31 (2). pp. 201-203. ISSN 21472092

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Abstract

Primary biliary cholangitis (PBC) is an autoimmune disease that is increasingly recognized as an important cause of chronic liver disease. Incidental diagnoses are not uncommon. We report a case of a middle-aged female with persistently elevated ALP activity. During the investigation of cholestasis, anti-mitochondrial antibodies (AMA) were detected in her serum. Ductular reaction with cholestasis was observed in the liver biopsy sample. Based on these findings, a diagnosis of PBC was established and ursodeoxycholic acid therapy was commenced. After several weeks of treatment, biochemical improvement was noted.

Item Type:	Article (Case Report)
Additional Information:	7124/83980
Uncontrolled Keywords:	Primary biliary cholangitis, anti-mitochondrial antibodies, ursodeoxycholic acid
Subjects:	Q Science > QR Microbiology > QR180 Immunology R Medicine > RB Pathology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Pathology & Lab Medicine
Depositing User:	Dr Norhidayah Kamarudin
Date Deposited:	02 Nov 2020 13:46
Last Modified:	20 Jan 2021 11:28
URI:	http://irep.iium.edu.my/id/eprint/83980

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