Cytopathological effects of smoking on clinically normal oral mucosa

Faisal, Ghasak Ghazi and Khalid, Faridah and Yazid, Yusri (2017) Cytopathological effects of smoking on clinically normal oral mucosa. In: 1st IIUM International Dental Conference 2017 in Commemoration of the Kulliyyah of Dentistry 10th Anniversary (1st IIDC), 6th-8th October 2017, Kuantan, Pahang. (Unpublished)

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Abstract

Introduction: Smoking is a well-known cause of oral disease and oral cancer. Several dysplastic cytological changes occur before the appearance of the clinical lesion. This study aimed to investigate the cytopathological effects of smoking in clinically normal oral mucosa of cigarette smokers. Materials and methods: A total of 40 cigarette smokers and 40 nonsmokers (control group) were included in this study. All participants had clinically normal oral mucosa. Oral smears were obtained from the side of the tongue and floor of the mouth using a Cytobrush. The smears were stained by Papanicolaou stain and examined under light microscope for inflammation, hyperkeratinization and dysplasia. Results: There was a significantly higher rate(p<0.005) of inflammation 63%, hyperkeratiniztion 62% and mild dysplasia 26% among smokers than non-smokers where the rates were 35%, 12% and 2% respectively. Conclusion: Smoking causes significant cytopathological changes in normal oral mucosa, the detection of which is important to prevent progression into carcinoma. The procedure is fast, painless and inexpensive.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	6388/59178
Uncontrolled Keywords:	Papanicolaou stain, brush biopsy, cigarette smokers, dysplasia, oral mucosa
Subjects:	R Medicine > RB Pathology R Medicine > RK Dentistry > RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry
Depositing User:	Assoc.Prof Ghasak Ghazi Al-Atrakchi
Date Deposited:	08 Nov 2017 15:08
Last Modified:	27 Nov 2017 11:36
URI:	http://irep.iium.edu.my/id/eprint/59178

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