The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom

Al-Ani, Imad Matloub Dally and Ismail, Soraya and Maung, Khin M. and Oothuman, Pakeer (2015) The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom. In: The 9th Scientific conference, College of Medicine, Al-Nahrain University, 21-22 December 2015, Baghdad, Iraq. (Unpublished)

Preview	PDF Download (151kB) | Preview
	PDF - Published Version Restricted to Repository staff only Download (586kB) | Request a copy

Abstract

Tamarind (Tamarindus indica) has been used as medical plant for treating many human and animal diseases and widely used as a traditional herbal medicine for the treatment of snake bites. The objective of the study is to investigate whether tamarind seed extract have neutralization activity on adverse histological reaction against venoms of the King Cobra. Twenty healthy mature male mice were randomly divided into 4 groups with 5 mice in each. The control group was injected with 1 ml of normal saline. The second group was injected subcutaneously with a single dose of 24.96µg/20g King Cobra venom (KCV) solution. The third group was injected with the same dose of KCV solution and 10mg/20g of Tamarind seed extract (TSE). The fourth group was injected with the same dose of KCV solution and 15mg/20g TSE solution. The animals were sacrificed after 24 hours of injection of the solution. Fragments of muscle, kidney and liver were fixed in 10% neutral buffered formalin, and processed for light microscopical studies. The result showed that TSE reduced the histopathological changes induced by the King Cobra venom in the muscles, livers and kidneys and the improvement was proportional to the applied dose of the TSE indicating that tamarind seed extract prevents adverse histological changes in the muscle, liver and kidney.

Item Type:	Conference or Workshop Item (Slide Presentation)
Additional Information:	5849/50960
Uncontrolled Keywords:	Tamarind, Tamarindus indica, venom, King Cobra
Subjects:	Q Science > QM Human anatomy R Medicine > RB Pathology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Basic Medical
Depositing User:	Assoc. Prof Dr.. Imad Matloub Dally Al-Ani
Date Deposited:	13 Jul 2016 15:28
Last Modified:	19 Jul 2016 09:14
URI:	http://irep.iium.edu.my/id/eprint/50960

Actions (login required)

View Item