Diffusion-reaction of substrate in immobilized slab biocatalyst for Michaelis-menten kinetics

Jameel, Ahmed Tariq and R Muhamad Fakih, RM Syibli Milasi (2011) Diffusion-reaction of substrate in immobilized slab biocatalyst for Michaelis-menten kinetics. In: Current research and development in biotechnology engineering at IIUM. IIUM Press, Kuala Lumpur, pp. 189-195. ISBN 9789674181444

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Abstract

The mass transfer effect on the overall reaction rate in a biocatalyst with a slab geometry containing an immobilized enzyme or cells has been investigated theoretically; Michaelis-Menten kinetics was studied. Numerical solution is used to solve the diffusion-reaction problem for Michaelis-Menten kinetics. The numerical scheme used was shooting method employing Runge-Kutta fourth order method for the solution of system of ODE-IVP. The numerical solution was validated by comparing with the exact solutions for the zero and first order reactions. A third order polynomial solution to the differential equation is also proposed. The approximate solution shows close agreement with the numerical solution within the range of parameters of practical significance. The concentration profiles within the catalyst slab were obtained as a function of Thiele modulus which in turn was used to evaluate effectiveness factor.

Item Type:	Book Chapter
Additional Information:	5642/20971
Uncontrolled Keywords:	Immobilized Biocatalyst, Effectlveness Factor, Michaelis-Menten Kinetics, Approximate Solution, Slab Geometry
Subjects:	T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User:	Dr. Ahmad Tariq Jameel
Date Deposited:	04 Jul 2012 10:25
Last Modified:	04 Jul 2012 10:25
URI:	http://irep.iium.edu.my/id/eprint/20971

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