Improvement of extraction processing conditions for antibacterial compounds from Curcuma longa

Ahmad Raus, Raha and Abdul Malek, Nur Farihah and Bastami, Mohd Saufi and Mat Amin, Noriha (2011) Improvement of extraction processing conditions for antibacterial compounds from Curcuma longa. In: Current Research and Development in Biotechnology Engineering at IIUM (volume II). IIUM Press, Kuala Lumpur, pp. 192-198. ISBN 978-967-418-151-2

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Abstract

Curcuma longa is a rhizomatous herbaceous perennial plant of the ginger family, Zingiberaceae that is known for its antibacterial property. In this study optimization of extraction processing conditions were detemlined to obtain maximum yield of antibacterial compounds from C. longa. Optimization experiments designed by Box-Behnken (Design Expert Software) were carried out with three parameters considered namely agitation, extraction time and temperature. Analysis of results was done statistically using Analysis of Yariance (ANDYA). The regression equation analysis showed that the optimum condition in producing antibacterial compound \vas 40°C of temperature, 24 hour and at 150 rpm agitation speed gave the maximum diameter of zone inhibition (19.17 mm). The analysis showed that the model (p < 0.01) is significant for inhibiting the bacterial activity.

Item Type:	Book Chapter
Additional Information:	3911/20793
Subjects:	T Technology > TP Chemical technology T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User:	Dr Raha Ahmad Raus
Date Deposited:	27 Nov 2012 14:27
Last Modified:	27 Nov 2012 14:27
URI:	http://irep.iium.edu.my/id/eprint/20793

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