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Integrating AI into infection control: evaluating the accuracy and consistency of four leading platforms across three regions

Julkipli, Julia and Alanazi, Alhanouf and Saw, Yen Tsen and Delport, Johan and Gupta, Ruchika and Silverman, Michael S. and Rahimi Shahmirzadi, MohammadReza and Zainulabid, Ummu Afeera and Elsayed, Sameer and AlMutawa, Fatimah (2026) Integrating AI into infection control: evaluating the accuracy and consistency of four leading platforms across three regions. Journal of the Association of Medical Microbiology and Infectious Disease Canada, 11 (2). pp. 134-140. E-ISSN 2371-0888

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Abstract

Background: Artificial Intelligence (AI) has emerged as a valuable tool in health care, supporting diagnostics and decision making. However, integration into clinical practice presents challenges, including data quality, accessibility, and regional guideline variations. This study evaluates four major AI platforms (ChatGPT, Meta AI, Copilot, and OpenEvidence) against CDC infection control guidelines for varicella and measles across Canada, Malaysia, and the United Kingdom. The objective was to assess the accuracy and consistency of AI responses on infection control measures compared with CDC guidelines and to evaluate how platforms handle complex scenarios. Methods: A comparative analysis of the four AI platforms was conducted using structured questions and clinical case scenarios on varicella and measles. Responses were evaluated for alignment with CDC guidelines. Platform accessibility was tested from Canada, Malaysia, and the United Kingdom, and regional variations were analyzed. Results: All platforms provided generally accurate information, but discrepancies were noted. ChatGPT and Meta AI mostly aligned with CDC guidelines, while OpenEvidence and Copilot omitted key epidemiological criteria. Meta AI lacked a full explanation of varicella laboratory criteria and was inaccessible in Malaysia. Regional differences in measles postexposure prophylaxis (PEP) were observed, particularly in Copilot and OpenEvidence. Response consistency varied between platforms. Conclusions: AI platforms show promise in supporting infection control but exhibit regional variability. Continued refinement of AI tools is essential to ensure their global applicability and accuracy. Consultation with an infection prevention and control (IPAC) physician remains vital for complex cases.

Item Type: Article (Journal)
Uncontrolled Keywords: artificial intelligence (AI), case definition, infection control measures, infectious period, Malaysia, measles, varicella
Subjects: R Medicine > RC Internal medicine > RC111 Infectious and Parasitic Diseases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Internal Medicine
Depositing User: Asst. Dr. Ummu Afeera Zainulabid
Date Deposited: 18 Jul 2026 08:00
Last Update: 18 Jul 2026 08:00
Queue Number: 2026-07-Q4026
URI: http://irep.iium.edu.my/id/eprint/129890

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