Ramya, Razanah and Othman, Rashidi and Mohd Hatta, Farah Ayuni (2026) Exploring the phytochemistry of Hanguana malayana (Jack) Merr. from Terengganu freshwater swamp in Malaysia. Tropical Journal of Natural Product Research, 10 (1). pp. 6455-6462. ISSN 2616-0684 E-ISSN 2616-0692
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Abstract
A freshwater shrub produces a wide range of bioactive compounds, and interest in utilizing its phytochemistry is growing rapidly. Meanwhile, exploiting phenolic compounds for the natural product industry could lead to more sustainable biochemistry studies. This study aimed to assess the phytochemistry of Hanguana malayana (Jack) Merr. from Terengganu freshwater swamps as potential pharmaceutical ingredients. Volatile compounds (GCTOF-MS analysis), phenolic acid profiles (HPLC analysis), and antimicrobial activities were determined in H. malayana leaf samples collected from freshwater swamp or heath forest in Terengganu, Malaysia. Using different solvents such as hexane, butanol, ethyl acetate, and ethanol extract, alkaline extraction was carried out. The GCTOF-MS findings determined 20 compounds from various chemical groups; nonetheless, just two phenolic compounds were found in the ethyl acetate (phenol and 2,4-bis(1,1-dimethylethyl)- (C14H22O)) and ethanol extracts (phenol (C6H6O)). The total phenolic compound content was 477.98±6.02 µg GAE/g DW. The highest phenolic acids were also identified, namely caffeic acid (3375.23 µg/g DW), coumaric acid (794.68 µg/g DW), ferulic acid (1333.33 µg/g DW), 2-coumaric acid (124.43 µg/g DW), as well as 3-coumaric acid (100.45 µg/g DW). The findings demonstrated that H. malayana antibacterial has strong antibacterial effects against S. aureus, S. epidermidis, E. coli, MRSA, and P. aeruginosa, as well as its antifungal activity against C. albicans, Fusarium sp., and M. gypsum. Therefore, H. malayana may have the potential to act as a source of valuable pharmaceuticals due to its phytochemical ingredients, which, at the same time, will be a vital aspect of ecological resilience.
| Item Type: | Article (Journal) |
|---|---|
| Uncontrolled Keywords: | Hanguana malayana, Freshwater, Aquatic plants, Phenolic, Heath forest, Antimicrobe, Swamp |
| Subjects: | BPC Science and Technology in Islam G Geography. Anthropology. Recreation > GE Environmental Sciences R Medicine > RS Pharmacy and materia medica S Agriculture > SD Forestry T Technology > TP Chemical technology T Technology > TP Chemical technology > TP248.13 Biotechnology T Technology > TP Chemical technology > TP934 Paints, pigments, varnishes, etc |
| Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Architecture and Environmental Design > Department of Landscape Architecture Kulliyyah of Architecture and Environmental Design |
| Depositing User: | Dr rashidi othman |
| Date Deposited: | 12 Feb 2026 11:13 |
| Last Modified: | 12 Feb 2026 11:13 |
| Queue Number: | 2026-02-Q2064 |
| URI: | http://irep.iium.edu.my/id/eprint/127325 |
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