Unlocking the therapeutic potential of the Genus Senecio (Asteraceae): essential oil composition and pharmacological insights

Salihu, Abu bakar Siddiq and Wan Salleh, Wan Mohd Nuzul Hakimi and Mohd Rahim, Faezatul Alwani and Mohd Zaini, Nur Nabilah and Arzmi, Mohd Hafiz (2025) Unlocking the therapeutic potential of the Genus Senecio (Asteraceae): essential oil composition and pharmacological insights. Rivista Italiana delle Sostanze Grasse, 102. pp. 43-57. ISSN 0035-6808

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Abstract

Senecio is the largest and most complex genus in the family of the Asteraceae with more than 1,500 species distributed widely throughout the world. A comprehensive search of the electronic databases (1986–2023) using the keywords of ‘Senecio’ and ‘essential oil’ revealed that an essential oils composition breakdown is available for 57 species, with α-pinene, α-farnesene, germacrene D, p-cymene, myrcene, α-terpinene, and caryophyllene oxide being the most identified components. The pharmacological activities have been summarized of different species including antimicrobial, antioxidant, repellent, antifungal, acaricidal, anti-inflammatory, cytotoxicity, phytotoxic, anticholinesterase, allelopathic, nematicidal, antimalarial, antileishmanial, α-glucosidase, anticorrosive, analgesic, and toxicity. This review is expected to lay the foundation for further studies of this genus and provides guidance for selecting accessions of species with the best chemical profiles.

Item Type:	Article (Review)
Additional Information:	7855/120602
Uncontrolled Keywords:	Asteraceae, Senecio, essential oil, composition, α-pinene, antimicrobial
Subjects:	Q Science > QR Microbiology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences
Depositing User:	AP Ts Dr Mohd Hafiz Arzmi
Date Deposited:	21 Apr 2025 15:46
Last Modified:	21 Apr 2025 15:48
URI:	http://irep.iium.edu.my/id/eprint/120602

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