Halmi, Husna Alia and Hilmi, Mohd Radzi and Md Rejab, Noor Shazana and Wolffsohn, James Stuart (2024) Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration. International Journal of Allied Health Sciences, 8 (5). pp. 242-249. E-ISSN 2600-8491
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Abstract
Background: This study was done to explore the possibility of the usage of different viscosities in artificial tears (Systane Ultra and Hydration) in detecting changes in corneal aberration on dry eye patients. Methods: 103 diagnosed dry eyes were observed in this study and two different artificial tears with different viscosities were instilled randomly in each eye. Corneal aberration measurement with Fourier index (Spherical aberration (SA), trefoil and coma) was then captured for 10 minutes using CASIA with a 1-minute time interval. Normal saline was instilled before the treatment was given (referred to as baseline). Repeated measure analysis of variance (RM ANOVA) and paired sample t-test were used to evaluate the effects of artificial tears after instillation and comparison between each specific time interval respectively. The P-value of 0.05 was set as the level of significance. Results: Corneal aberration with artificial tears was then compared to normal saline and the results showed that there was no significant difference between artificial tears in terms of retention time after 10 minutes (p>0.05) in dry eye participants. Both groups demonstrated significant improvements from baseline and there was a significant difference from baseline (p<0.05). Conclusion: Instillation of high viscous artificial tear produce better uniformity of the corneal surface resulting in lower corneal aberration.
| Item Type: | Article (Journal) |
|---|---|
| Uncontrolled Keywords: | Corneal aberration; Systane Ultra, Systane Hydration; Tear retention time |
| Subjects: | R Medicine > RE Ophthalmology |
| Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Allied Health Sciences Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science |
| Depositing User: | Dr Mohd Radzi Hilmi |
| Date Deposited: | 06 Jan 2025 12:26 |
| Last Modified: | 06 Jan 2025 12:26 |
| URI: | http://irep.iium.edu.my/id/eprint/117399 |
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