Ethnomedicine: extraction of acacia auriculiformis leaves and phenolic compounds screening for pharmacological uses

Ramya, Razanah and Othman, Rashidi and Mohd Hatta, Farah Ayuni and Wan Sulaiman, Wan Syibrah Hanisah and Mohd Latiff, Nur Hanie (2024) Ethnomedicine: extraction of acacia auriculiformis leaves and phenolic compounds screening for pharmacological uses. In: 12th International Conference on Ecology, Human Habitat and Environmental Change in Malay World, 25-26 Jul 2024, Batam, Indonesia.

Preview	PDF (Abstract) - Supplemental Material Download (1MB) | Preview
	PDF (Proceeding Paper) - Published Version Restricted to Registered users only Download (1MB) | Request a copy

Abstract

Acacia auriculiformis, sometimes known as akasia kuning by the Malay, is a globally widespread tree with a diverse variety of therapeutic properties. Traditionally, it has been used to address a range of medicinal issues, including the use of the root to alleviate aches, pains, and sore eyes and the use of the bark to cure rheumatism. The phytochemicals found in different portions of plants have significant potential to function as medicinal remedies for various ailments and exhibit pharmacological effects. However, there is a lack of studies reported on A. auriculiformis leaf. This research aims to examine the phenolic compounds and determine the antibacterial activity of the leaf extract from A. auriculiformis. The leaf extract of A. auriculiformis was extracted with aqueous extraction before being re-extracted using different solvent polarities:petroleum ether, ethyl acetate, and butanol. Then, the extract was subjected to chromatographic analysis to determine its functional group using FT-IR and its phenolic content using HPLC. The antibacterial activity was assessed using the disc diffusion technique. The analysis revealed the existence of an aliphatic hydrocarbon at a wavelength of 2927.49 cm1 in A. auriculiformis. The leaf extract had a total phenolic content of 409.18 μg GAE/g DW, and four phenolic acids were identified: 4- Hydroxybenzoic acid, Caffeic acid, trans-p-Coumaric acid, and Vanillic acid. The A. auriculiformis leaf extract exhibited high antibacterial activity, as evidenced by the presence of inhibition zones measuring between 3 and 10 mm for all investigated bacterial pathogens (S. aureus, S. epidermidis, E. coli, MRSA, and P. aeruginosa). Overall, the leaves of A. auriculiformis demonstrate promise as a possible source of phenolic compounds and exhibit significant antibacterial activity, indicating their potential use in producing these compounds.

Item Type:	Proceeding Paper (Plenary Papers)
Uncontrolled Keywords:	akasia kuning; ethnomedicine; natural product; phytochemical; pharmacology; phenolic compounds.
Subjects:	G Geography. Anthropology. Recreation > GE Environmental Sciences G Geography. Anthropology. Recreation > GR Folklore R Medicine > RS Pharmacy and materia medica S Agriculture > S Agriculture (General) S Agriculture > SD Forestry T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Architecture and Environmental Design > Department of Landscape Architecture Kulliyyah of Architecture and Environmental Design
Depositing User:	Dr rashidi othman
Date Deposited:	19 Sep 2024 11:09
Last Modified:	19 Sep 2024 11:17
URI:	http://irep.iium.edu.my/id/eprint/114463

Actions (login required)

View Item