Subclinical hypothyroidism and placenta abruption: a dangerous relationship during pregnancy

Zainoren, Nadirah and Said, Abdul Hadi (2024) Subclinical hypothyroidism and placenta abruption: a dangerous relationship during pregnancy. Borneo Journal of Medical Sciences, 18 (3). pp. 207-212. ISSN 1985-1758 E-ISSN 2710-7353

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Abstract

This case report explores the intricate link between subclinical hypothyroidism and placenta abruption during pregnancy, emphasising the potential risks and clinical implications, through a detailed case study of a 28-year-old woman with a history of hyperthyroidism, non-compliance, and subsequent subclinical hypothyroidism, causing placenta abruption leading to intrauterine death. The report highlights the challenges in managing thyroid disorders during pregnancy. Limited Malaysian data on this association prompts a broader discussion of international findings, suggesting a correlation between subclinical hypothyroidism and adverse pregnancy outcomes. The study delves into potential mechanisms, including thyroid hormone impact on placental vascular function and the complexity added by autoimmune thyroiditis. Personalised treatments, thyroid function monitoring, and comprehensive antenatal care are emphasised for optimal pregnancy outcomes. This case underscores the need for increased awareness, proactive management, and preconception counselling to safeguard maternal and foetal well-being.

Item Type:	Article (Case Report)
Uncontrolled Keywords:	Hypothyroidism, Pregnancy, Placenta abruption, Pregnancy outcomes
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine R Medicine > RG Gynecology and obstetrics R Medicine > RJ Pediatrics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011) Kulliyyah of Medicine
Depositing User:	SR NUR FARHANA LATFI
Date Deposited:	03 Sep 2024 11:13
Last Modified:	03 Sep 2024 11:13
URI:	http://irep.iium.edu.my/id/eprint/114222

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