Application of chromatographic and spectroscopic-based methods for analysis of omega-3 (ω-3 FAs) and omega-6 (ω-6 FAs) fatty acids in marine natural products

Rohman, Abdul and Irnawati, Irnawati and Windarsih, Anjar and Riswanto, Florentinus Dika Octa and Indrayanto, Gunawan and Riyanto, Sugeng and Ahmad Fadzillah, Nurrulhidayah and Abu Bakar, Nor Kartini (2023) Application of chromatographic and spectroscopic-based methods for analysis of omega-3 (ω-3 FAs) and omega-6 (ω-6 FAs) fatty acids in marine natural products. Molecules, 28 (14). pp. 1-20. E-ISSN 1420-3049

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Abstract

Abstract: Omega-3 fatty acids v(ω-3 FAs) such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) and omega-6 fatty acids (ω-6 FAs) such as linoleic acid and arachidonic acid are important fatty acids responsible for positive effects on human health. The main sources of ω-3 FAs and ω-6 FAs are marine-based products, especially fish oils. Some food, supplements, and pharmaceutical products would include fish oils as a source of ω-3 FAs and ω-6 FAs; therefore, the quality assurance of these products is highly required. Some analytical methods mainly based on spectroscopic and chromatographic techniques have been reported. Molecular spectroscopy such as Infrared and Raman parallel to chemometrics has been successfully applied for quantitative analysis of individual and total ω-3 FAs and ω-6 FAs. This spectroscopic technique is typically applied as the alternative method to official methods applying chromatographic methods. Due to the capability to provide the separation of ω-3 FAs and ω-6 FAs from other components in the products, gas and liquid chromatography along with sophisticated detectors such as mass spectrometers are ideal analytical methods offering sensitive and specific results that are suitable for routine quality control.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Keywords: spectroscopic techniques; omega-3 fatty acids; ω-6 FAs; chemometrics; quality control; chromatographic methods
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	International Institute for Halal Research and Training (INHART)
Depositing User:	Dr Nurrulhidayah Ahmad Fadzillah
Date Deposited:	15 Feb 2024 12:32
Last Modified:	15 Feb 2024 12:32
URI:	http://irep.iium.edu.my/id/eprint/110863

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