Screening of fatty acid compound of S. polycystum for anti-cariogenic potential

Zamimi, Nurul Najwa and Ab. Halim, Noorhazayti and Lestari, Widya and Darnis, Deny Susanti and Wan Ishak, Wan Mohd Faizal and Md Mustafa, Md Muziman Syah (2017) Screening of fatty acid compound of S. polycystum for anti-cariogenic potential. In: 1st IIUM International Dental Conference 2017 in Commemoration of the Kulliyyah of Dentistry 10th Anniversary (1st IIDC), 6th-8th October 2017, Kuantan, Pahang, Malaysia. (Unpublished)

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Abstract

Dental caries is the most common yet preventable disease. Study found that seaweed exhibits anti-cariogenic properties. However, little attention have been given to the study on anti-cariogenic properties of seaweed and the bioactive compound that responsible for the anti-cariogenic activities have not adequately investigated. This study was conducted to evaluate the best extraction methods for S. polycystum and to determine the fatty acid compounds of S. polycystum that have anti-cariogenic potential against oral cariogenic bacteria. Dried seaweeds were extracted by soxhlet using three different solvents (methanol, dichloromethane and hexane). The crude extracts were kept in a close container at -20 degree Celsius. The bioactive compound of the crude extract of seaweeds was analyzed using Gas Chromatography Mass Spectrometer (GCMS).Highest extraction yield in S. polycystum was produced by methanol extraction followed by hexane and dichloromethane. GCMS analysis revealed that the presence of palmitic acid (18.02%) as major compound, followed by oleic acid (8.44%), lauric acid (5.23%), myristic acid (3.60%), heptadecanoic acid (2.23%), 9-hexadenoic acid (1.82%) and the lowest is 2-methylhexadecan-1-ol (1.75%). At the end of this study, it is found that, methanol extraction is the most efficient solvent as it produced the highest extraction yield in S. polycystum. Lauric acid, palmitic acid, myristic acid and oleic acid detected in S. polycystum have been reported to exhibit antimicrobial activities thus proved the potentiality of S. polycystum as anti-cariogenic agent.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	5869/76418
Uncontrolled Keywords:	Fatty acid; Sargassum polycystum; anti-cariogenic; Dentistry
Subjects:	R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences Kulliyyah of Dentistry > Department of Paediatric Dentistry and Dental Public Health Kulliyyah of Science Kulliyyah of Allied Health Sciences
Depositing User:	Asst Prof Noorhazayti Ab. Halim
Date Deposited:	19 Dec 2019 13:01
Last Modified:	26 Apr 2022 08:40
URI:	http://irep.iium.edu.my/id/eprint/76418

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