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Carotenoid and chlorophyll profiles in five species of Malaysian seaweed as potential Halal Active Pharmaceutical Ingredient (API)

Othman, Rashidi and Md Amin, Nur Alifah and Abu Bakar, Ainaa Eliah (2018) Carotenoid and chlorophyll profiles in five species of Malaysian seaweed as potential Halal Active Pharmaceutical Ingredient (API). In: International Conference on Halal Innovation in Products and Services 2018 (i-CHIPS 2018), 13th-14th July 2018, Haat Yai, Songkhla, Thailand.

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Abstract

Seaweed, also known as macroalgae, has been gaining the interest of researchers due to the presence of functional bioactive compounds that can be extracted from their biomass. This research aimed to explore the chlorophyll and carotenoid content from five species of Malaysian seaweed as potential Active Pharmaceutical Ingredient (API). Three species of red macroalgae (E. denticulatum, G. tikvahiae, and K. striatum), green macroalgae (C. lentillifera) and one brown macroalga (P. pavonica) were studied to determine their chlorophyll and carotenoid content by using UV-Vis spectrophotometer and HPLC. Their antioxidant properties were measured by using DPPH Radical Scavenging activity and antimicrobial activities were investigated by Disc Diffusion method. In terms of carotenoid content, P. pavonica contained the highest amount of carotenoid (100.89 ± 14.71 µg/g DW) and chlorophyll content (7.52 ±1.51 µg/g DW). Meanwhile, individual carotenoid content showed K. striatum had the highest lutein content (38.6 µg/g DW). Zeaxanthin, beta-carotene, and violaxanthin showed the highest amount in C. lentillifera at 21.30 µg/g DW, 10.70 µg/g DW, and 8.93 µg/g DW respectively. In addition, the antioxidant test showed that P. pavonica presented the strongest DPPH activity with the percentage of inhibition (i%) of (61.0% ± 0.9). Finally, strong antimicrobial activities were shown by seaweed samples toward E. coli and P. aerugenosa. All seaweed samples demonstrated moderate antifungal samples towards M. gypseum and Fusarium sp.

Item Type: Conference or Workshop Item (Speech/Talk)
Additional Information: 3842/65294
Uncontrolled Keywords: Carotenoid, chlorophyll, Malaysian seaweed, Halal Active Pharmaceutical Ingredient (API)
Subjects: R Medicine > RS Pharmacy and materia medica
S Agriculture > SB Plant culture
T Technology > TP Chemical technology > TP248.13 Biotechnology
T Technology > TP Chemical technology > TP934 Paints, pigments, varnishes, etc
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Architecture and Environmental Design > Department of Landscape Architecture
Depositing User: Dr rashidi othman
Date Deposited: 24 Aug 2018 10:37
Last Modified: 24 Aug 2018 10:37
URI: http://irep.iium.edu.my/id/eprint/65294

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