Proteins are potent biomarkers to detect colon cancer progression

Kuppusamy, Palaniselvam and Govindan, Natanamurugaraj and Mohd Yusoff, Mashitah and Arief Ichwan, Solachuddin Jauhari (2017) Proteins are potent biomarkers to detect colon cancer progression. Saudi Journal of Biological Sciences, 24 (6). pp. 1212-1221. ISSN 1319-562X

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Abstract

Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. Thus, in this review we demonstrate the important protein biomarker in colon cancer development and molecular identification of protein biomarker discovery.

Item Type:	Article (Journal)
Additional Information:	5731/40416
Uncontrolled Keywords:	Colon cancer; Biomarkers; Secretory proteins; Proteomic techniques
Subjects:	R Medicine > RB Pathology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry
Depositing User:	Dr. Solachuddin J.A. Ichwan
Date Deposited:	21 Mar 2016 14:57
Last Modified:	20 Sep 2017 15:24
URI:	http://irep.iium.edu.my/id/eprint/40416

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