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Study on anti-bacterial potentials of some Malaysian brown seaweeds

Jaswir, Irwandi and Tawakalit Tope, Asiyanbi-Hammed and Ahmad Raus, Raha and A. Monsur, Hammed Ademola and Ramli, Nazaruddin (2014) Study on anti-bacterial potentials of some Malaysian brown seaweeds. Food Hydrocolloids, 42 (P2). pp. 275-279. ISSN 0268-005X

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Abstract

With increasing in emergence of resistance pathogenic microorganisms to majority of antibiotics, there is an urgent and continuous need for exploring and developing cheaper and effective plant based drugs with better bioactive potential and least side effects. Bioactive extracts from four species of brown seaweeds (Sargassum plagyophillum, Sargassum flavellum, Padina australis and Sargassum binderi) of Malaysia origin were tested in vitro for their anti-bacterial activities against gram positive bacteria (Bacillus subtilis and Staphylococcus aureus) and gram negative bacteria (Pseudomonas aeruginosa and Escherichia coli). Four solvents (methanol, acetone, ethyl acetate and chloroform) were used during the preliminary screening stage to obtain crude extracts. None of the crude extracts displayed antimicrobial activity against the gram negative bacteria while the gram positive bacteria were inhibited. Methanol extract of S. plagyophillum was the best in terms of yield (4.72%) and antimicrobial activity with inhibition zone of 12 mm against B. subtilis. Chloroform fraction gave highest inhibition zone of 17 mm against B. subtilis. Hence, the result from this work showed that S. plagyophillum has the potential for antimicrobial drug production.

Item Type: Article (Journal)
Additional Information: 5784/39291
Uncontrolled Keywords: Anti-inflammatory; Cytotoxicity; Nitric oxide; Seaweed; Sulfated polysaccharide; Anti-bacterial activities; Inhibition zone
Subjects: T Technology > TP Chemical technology
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes: International Institute for Halal Research and Training (INHART)
Kulliyyah of Engineering
Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Dr Irwandi Jaswir
Date Deposited: 18 Nov 2014 07:58
Last Modified: 23 May 2018 13:47
URI: http://irep.iium.edu.my/id/eprint/39291

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