Pilot study on prevalence of enamel erosion in patients having gastroesophageal reflux disease (GERD) attending IIUM dental clinic

Ahmad Tajudin, Ahmad Nur Hilmi and Aminuddin, Aiman Za'im and Alfarisi, Hamad and Mustafa Al-Ahmad, Basma Ezzat and Mustafa, Nazih Shaban and Md Jalil, Muhammad Ateeq (2025) Pilot study on prevalence of enamel erosion in patients having gastroesophageal reflux disease (GERD) attending IIUM dental clinic. Annals of Dentistry, 32 (8). pp. 48-53. ISSN 0128-7532 E-ISSN 2462-2060

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Abstract

Gastroesophageal reflux disease (GERD) is a common digestive disorder that affects millions of people worldwide. Reflux of gastric acid may cause oral acidification that can induce teeth demineralization. Destruction of dental hard tissue by acid reflux necessitates a combine approach involving medical and dental profession. This pilot study aims to assess association between enamel erosion and GERD, and estimate prevalence of enamel erosion among GERD patients. A total of 22 patients (GERD and control) were involved in this case-control study. Dental charting was done using five-point ordinal scales of modified Tooth Wear Evaluation System (TWES 2.0). Cohen’s Kappa Coefficient was used for assessment of intra-rater and inter-rater reliability. Fisher’s Exact Test was used to determine association between enamel erosion and GERD, reflecting prevalence. Out of 11 GERD patients, 63.6% exhibit enamel erosion, whereas only 9.1% of control patient presented with enamel erosion. Fisher’s Exact Test showed a significant prevalence of enamel erosion in GERD patients (p=0.024). This study showed a clear association between enamel erosion and GERD, and it can be considered as an oral manifestation in patient with GERD. Future study involving large sample size is recommended to show clear statistical evidence of association between enamel erosion and GERD.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Gastroesophageal Reflux Disease (GERD), enamel erosion, prevalence
Subjects:	R Medicine > RK Dentistry R Medicine > RK Dentistry > RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences Kulliyyah of Dentistry > Department of Oral Maxillofacial Surgery and Oral Diagnosis Kulliyyah of Medicine Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Dr. Hamad Abdulsalam Hamad Alfarisi
Date Deposited:	31 Dec 2025 09:34
Last Modified:	31 Dec 2025 09:34
Queue Number:	2025-12-Q1375
URI:	http://irep.iium.edu.my/id/eprint/126518

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