An in vivo biocompatible study of antimicrobial biocomposite membrane: preliminary outcome

Mohd Zohari, Sarah Haryati and Zulkifly, Ahmad Hafiz and Abd Jalil, Rosnani and Mohd Jan, Nurul Hafiza and Zainal Abdullah, Muhamad Ezham and Che Seman, Che Nor Zarida and Ibrahim, Mohd Zulfadzli and Abd Hamid, Zahana (2021) An in vivo biocompatible study of antimicrobial biocomposite membrane: preliminary outcome. In: 50th Malaysian Orthoapedic Association Annual Scientific Meeting 2021, 22-26 Jun 2021, Virtual. (Unpublished)

Preview	PDF (Acceptance Letter) Download (109kB) | Preview
	PDF (Poster Presentation) - Presentation Restricted to Registered users only Download (17MB) | Request a copy

Abstract

Guided Bone Regeneration (GBR) is a surgical procedure that uses barrier membranes to treat bony defects. The membrane plays an important role in proper bone regeneration. A triple-layered membrane containing poly (lactic-co-glycolic acid) (PLGA) matrix with bioactive apatite filling and lauric acid (LA), which is a naturally derived antimicrobial substance is one of the examples of membrane used. Critical Size Defect (CSD) is an experimental method in evaluating the effectiveness of newly developed biomaterials to stimulate bone formation before clinical application. New Zealand White Rabbits (Oryctolagus cuniculus) are commonly used rabbits for laboratory research and industry toxicology studies. By using the CSD technique in the New Zealand White Rabbit, this study seeks to investigate the biocompatibility and new bone growth potential of the bio composite membrane through in vivo analysis.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	4820/91148
Uncontrolled Keywords:	Critical size defect (CSD), biocomposite membrane, toxicology
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Department of Orthopaedics, Traumatology & Rehabilitation Kulliyyah of Medicine
Depositing User:	Sr Che Nor Zarida Che Seman
Date Deposited:	30 Jul 2021 12:20
Last Modified:	30 Jul 2021 12:20
URI:	http://irep.iium.edu.my/id/eprint/91148

Actions (login required)

View Item