The blood glucose lowering effect of Malaysian Tinospora crispa in rats

Firdausa, Sarah and Cho, Maung Maung and Khin, Maung Maung and Win @ Fahmida, Nilar and Ku Zaifah, Norsidah and Suryawati, Suryawati (2020) The blood glucose lowering effect of Malaysian Tinospora crispa in rats. Jurnal Natural, 20 (1). pp. 20-23. ISSN 1411-8513 E-ISSN 2541-4062

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Abstract

Diabetes is defined as a chronic hyperglycemia which should be countered by the effective, safe and readily available hypoglycemic agents. Herbal is among alternatives that have been used by society for years but lacks of documented evidences. Tinospora crispa (TC) is enriched by phytochemicals which potentially reduce blood glucose thus is useful for diabetic patients. This study aimed to investigate the potency of TC in reducing blood sugar and body weight. It involved 30 healthy rats divided into 5 groups namely: normal control, normal fed with TC extract, diabetic, TC-treated diabetic (dose 500 mg/kg w/w), and vitamin E-treated diabetic rats (60 IU). The body weight and fasting blood glucose were measured each week for 1 month. The administration of TC extract 500 mg/kg (w/w) helps to maintain body weight in diabetic rats and reduce the fasting blood glucose. TC is highly potent as hypoglycemic agents therefore needed to be explored further.

Item Type:	Article (Journal)
Additional Information:	3253/85405
Uncontrolled Keywords:	Tinospora crispa (TC), fasting blood glucose, body weight
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Basic Medical Kulliyyah of Medicine
Depositing User:	Mrs Norsyafini Ahmad Marzuki
Date Deposited:	30 Nov 2020 16:11
Last Modified:	30 Nov 2020 16:11
URI:	http://irep.iium.edu.my/id/eprint/85405

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