Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial

Muhd Helmi, Muhd Alwi and Hussain, Suhaimi and Bachok, Norsaadah (2019) Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial. In: Diabetes Asia 2019 Conference, 10th -13th October 2019, Hotel Istana, Kuala Lumpur. (Unpublished)

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Abstract

Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between continuous glucose monitoring system (CGMS) and self-monitoring blood glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children.

Item Type:	Conference or Workshop Item (Slide Presentation)
Additional Information:	7715/82430
Uncontrolled Keywords:	CGMS, SMBG, Type 1 Diabetes
Subjects:	R Medicine > RJ Pediatrics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Paediatrics Kulliyyah of Medicine
Depositing User:	Dr Muhd Alwi Muhd Helmi
Date Deposited:	28 Aug 2020 09:49
Last Modified:	28 Aug 2020 09:49
URI:	http://irep.iium.edu.my/id/eprint/82430

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