Hilles, Ayah Rebhi and Mahmood, Syed and Kaderi, Mohd Arifin and Hashim, Ridzwan (2019) Identification of the bioactive compounds of skin mucus from asian swamp eel (monopterus albus) using liquid chromatography quadrupole-time-of-flight mass spectrometry. Malaysian Journal of Biochemistry and Molecular Biology, 22 (3). pp. 43-47. ISSN 1511-2616 E-ISSN 2600-9005
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Abstract
Asian swamp eels have been widely accepted as sources of food, especially among various Asian cultures. However, their potential values as novel sources of therapeutic agents have not been widely appreciated. Like most other tropical fishes and amphibians, the outer integumentary system of Monopterus albus is covered with mucus layers, which may act as a mechanical and biochemical barrier for their skin. The biochemical components of these mucus layers may have certain compounds that may be medically beneficial to human. The current study was interested to screen the bioactive compounds of skin mucus from the tropical Asian swamp eel (Monopterus albus) using Liquid Chromatography Quadrupole-Time-Of-Flight Mass Spectrometry (LC-QTOF-MS), for this purpose, eel skin mucus extract was used for LC-QTOF-MS analysis. The screening results for the bioactive compounds revealed different bioactive compounds which possess multiple biological properties mainly anticancer, antimicrobial, anti-inflammatory and antioxidant activities. In conclusion, the current study illustrated that eel skin mucus contain different bioactive compounds which might be consider as therapeutic-promising agents.
| Item Type: | Article (Journal) |
|---|---|
| Additional Information: | 4643/82172 |
| Uncontrolled Keywords: | Monopterus albus, bioaactive compounds, eel skin mucus, Liquid Chromatography Quadrupole-Time-Of-Flight Mass Spectrometry |
| Subjects: | Q Science > Q Science (General) R Medicine > RS Pharmacy and materia medica > RS192 Materia Medica-Pharmaceutical Technology R Medicine > RS Pharmacy and materia medica > RS403 Materia Medica-Pharmaceutical Chemistry |
| Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Allied Health Sciences Kulliyyah of Allied Health Sciences > Department of Biomedical Science (Effective:1st July 2011) |
| Depositing User: | Dr Mohd. Arifin Bin Kaderi |
| Date Deposited: | 14 Aug 2020 11:42 |
| Last Modified: | 14 Aug 2020 11:42 |
| URI: | http://irep.iium.edu.my/id/eprint/82172 |
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