Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society

Rajadurai, Pathmanathan and Cheah, Phaik Leng and How, Soon Hin and Liam, Chong Kin and Ahmad Annuar, Muhammad Azrif and Omar, Norhayati and Othman, Noriah and Mohd Marzuki, Nurhayati and Pang, Yong Kek and Ahmad Bustamam, Ros Suzanna and Tho, Lye Mun (2019) Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society. Lung Cancer, 136. pp. 65-73. ISSN 0169-5002

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Abstract

In the recent years, increased understanding of the molecular profiles of non-small cell lung cancer (NSCLC) has allowed for targeted treatment of actionable genetic mutations. The management of NSCLC now requires multiple molecular tests to guide the treatment strategy. In the light of this, there is a need to establish a molecular testing consensus statement for advanced NSCLC patients in Malaysia. This Malaysian consensus statement was developed by a panel of experts, chaired by a pathologist and composed of three other pathologists, four respiratory physicians and three oncologists. It reflects currently available scientific data and adaptations of recommendations from international guidelines to the local landscape. Expert recommendations on different aspects of molecular testing agreed upon by the panel are provided as structured discussions. These recommendations address the appropriate patients and samples to be tested, as well as when and how these tests should be performed. The algorithms for molecular testing in metastatic NSCLC, in the first line setting and upon disease progression beyond first line therapy, were developed.

Item Type:	Article (Review)
Additional Information:	2987/79720
Uncontrolled Keywords:	Non-small cell lung cancerGuidelinesTissue biopsyMolecular testingTargeted therapy
Subjects:	R Medicine > RC Internal medicine R Medicine > RC Internal medicine > RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine
Depositing User:	AP Soon Hin How
Date Deposited:	21 Mar 2020 00:00
Last Modified:	21 Mar 2020 00:00
URI:	http://irep.iium.edu.my/id/eprint/79720

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