Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS

Alara, Oluwaseun Ruth and Abdurahman, Nour Hamid and Ukaegbu, Chinonso Ishmael and Azhari, Nour Hamid and Kabbashi, Nassereldeen Ahmed (2018) Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS. Journal of Liquid Chromatography & Related Technologies. pp. 1-10. ISSN 1082-6076 E-ISSN 520-572X (In Press)

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Abstract

The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance.

Item Type:	Article (Journal)
Additional Information:	4286/66702
Uncontrolled Keywords:	Alkaloids, Flavonoids, Mass spectrometry, Saponins, Terpenoids, Vernonia cinerea
Subjects:	T Technology > TP Chemical technology > TP155 Chemical engineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User:	Dr Nassereldeen Kabbashi
Date Deposited:	18 Oct 2018 11:03
Last Modified:	18 Oct 2018 11:03
URI:	http://irep.iium.edu.my/id/eprint/66702

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