Mohamad Fauzi, Nor Farah and Che Hasan, Muhammad Kamil and Henry Joseph, Leonard (2014) Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk. Obesity Reviews, 15 (Supplementary 2). p. 70. ISSN 1467-789X
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Abstract
Studies have shown that visceral adiposity index (VAI) reflects metabolic disturbances and cardiometabolic risk, both of which are associated with lower physical functions. This study aimed to evaluate the associations of VAI with physical functions (i.e. cardiorespiratory fitness, balance, grip strength) and cardiometabolic parameters in older adults. Sixty, physically inactive men and women (n male = 35, age: 60.2 ± 4.4 years, BMI: 28.8 ± 4.6 kg/m2), underwent (1) anthropometric measurements; (2) 6-minute walk test, timed up-and-go and hand grip tests; (3) assessment of plasma insulin, glucose, triglycerides, HDL, adiponectin, and highsensitivity C-reactive protein (hs-CRP). VAI was estimated using anthropometric (BMI and waist circumference) and biochemical (triglycerides and HDL) parameters. Insulin resistance was calculated as HOMA-IR index. Partial correlations analysis controlled for gender demonstrated positive associations for VAI with insulin resistance (r = 0.658, p < 0.001) and hs-CRP (r = 0.325, p = 0.012). No association between VAI and physical function parameters was observed. In addition, waist circumference was inversely correlated with plasma adiponectin (r = −0.297, p = 0.023). Multivariate regression analysis revealed that only insulin resistance was an independent predictor of VAI. This study suggests that VAI is a strong indicator of deterioration in insulin sensitivity, and is associated with hs-CRP but not physical functions in older adults.
Item Type: | Article (Review) |
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Additional Information: | 5711/59766 |
Uncontrolled Keywords: | Visceral adiposity; Associations with physical functions; cardiometabolic risk |
Subjects: | Q Science > Q Science (General) R Medicine > RT Nursing R Medicine > RT Nursing > RT71 Study and Teaching |
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Nursing > Department of Medical Surgical Nursing |
Depositing User: | Dr Muhammad Kamil Che Hasan |
Date Deposited: | 07 Dec 2017 17:50 |
Last Modified: | 07 Dec 2017 17:50 |
URI: | http://irep.iium.edu.my/id/eprint/59766 |
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