Statins and ischaemia reperfusion injury: a molecular biological review

Abdul Rahman, Mohd Norhisham Azmi and Chetter, Ian Clifford (2010) Statins and ischaemia reperfusion injury: a molecular biological review. Current Vascular Pharmacology, 8 (6). pp. 831-835. ISSN 1570-1611 E-ISSN 1875-6212

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Abstract

The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the effect of ischaemia reperfusion injury. This review considers the biomolecular processes that may lead to this beneficial effect.

Item Type:	Article (Journal)
Additional Information:	6953/59118
Uncontrolled Keywords:	Ischaemia reperfusion injury, statins
Subjects:	R Medicine > RD Surgery
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Surgery
Depositing User:	Dr M N A Abdul Rahman
Date Deposited:	06 Nov 2017 15:28
Last Modified:	06 Nov 2017 15:28
URI:	http://irep.iium.edu.my/id/eprint/59118

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