Shahadan, Siti Zuhaidah and Daud, Azlina and Md. Isa, Muhammad Lokman and Mohd Rasani, Ali Aminuddin and Ibrahim, Muhammad and Draman, Samsul (2018) Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia. International Medical Journal Malaysia, 17 (1). pp. 79-86. E-ISSN 1823-4631
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Abstract
Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang. Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level. Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043). Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings.
Item Type: | Article (Journal) |
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Additional Information: | 5226/58135 |
Uncontrolled Keywords: | obesity, inflammation, adults |
Subjects: | R Medicine > RT Nursing |
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Nursing |
Depositing User: | Assist. Prof. Dr. Azlina Daud |
Date Deposited: | 05 Sep 2017 12:02 |
Last Modified: | 24 Jan 2019 09:42 |
URI: | http://irep.iium.edu.my/id/eprint/58135 |
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