Ahmad Zaiki, Farah Wahida and Md Dom, Sulaiman
(2014)
The effect of prenatal ultrasound heating throughout gestation on rabbit fetal weight.
International Journal of Bio-Science and Bio-Technology, 6 (3).
pp. 71-80.
ISSN 2233-7849
Abstract
The aim of this in vivo experimental study is to determine the association between
ultrasound exposure time and rabbit fetal weight. A total of 14 pregnant does were exposed to
ultrasound heating for 30, 60, and 90 minutes of ultrasound exposure at their middle of each
gestational stage, while another 4 pregnant does served as control. Total of 136 fetuses (1st
stage, n=34 (25%); 2nd stage, n=28 (20.6%); 3rd stage, n=74 (54.4%)) were analyzed for
fetal body weight. There were significant differences in fetal weight at all stages (p<0.05;
95% CI do not cross 0) of all groups at different length of exposure time. There were also
negative correlation between groups with different exposure durations and fetal weight in the
1st and the 3rd stage (p<0.05; r = -0.40, p<0.05; r = -0.23 respectively). Exposure time was
found poorly associated with fetal weight in the 1st and the 3rd stage (p<0.05; r2 = 0.15 and
0.04 respectively). This study suggests the heating effect of ultrasound exposure might act as
a noxious agent that promotes intrauterine growth restriction in developing fetus that might
consequently impacts the rabbit fetal weight. Therefore a considerably increase in awareness
of negligible effects aroused from prenatal ultrasound exposure was concerned as it was
widely applied to pregnant women.
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