Dynamic screening of autistic children in various mental states using pattern of connectivity between brain regions

Khosrowabadi, Reza and Quek, Chai and Kai, Keng Ang and Abdul Rahman, Abdul Wahab and Annabel Chang, Shen-Sing (2015) Dynamic screening of autistic children in various mental states using pattern of connectivity between brain regions. Applied Soft Computing, 32. pp. 335-346. ISSN 1568-4946

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Abstract

In this study, a dynamic screening strategy is proposed to discriminate subjects with autistic spectrum disorder (ASD) from healthy controls. The ASD is defined as a neurodevelopmental disorder that disrupts normal patterns of connectivity between the brain regions. Therefore, the potential use of such abnormality for autism screening is investigated. The connectivity patterns are estimated from electroencephalogram (EEG) data collected from 8 brain regions under various mental states. The EEG data of 12 healthy controls and 6 autistic children (age matched in 7–10) were collected during eyes-open and eyes-close resting states as well as when subjects were exposed to affective faces (happy, sad and calm). Subsequently, the subjects were classified as autistic or healthy groups based on their brain connectivity patterns using pattern recognition techniques. Performance of the proposed system in each mental state is separately evaluated. The results present higher recognition rates using functional connectivity features when compared against other existing feature extraction methods.

Item Type:	Article (Journal)
Additional Information:	6145/49856
Uncontrolled Keywords:	Autism screening; EEG; Connectivity feature; Affective face perception; Pattern recognition
Subjects:	T Technology > T Technology (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Information and Communication Technology > Department of Information System Kulliyyah of Information and Communication Technology > Department of Information System
Depositing User:	Prof Abdul Wahab Abdul Rahman
Date Deposited:	20 May 2016 14:59
Last Modified:	05 Dec 2016 16:28
URI:	http://irep.iium.edu.my/id/eprint/49856

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