α-glucosidase and 15-lipoxygenase inhibitory activities of phytochemicals from calophyllum symingtonianum

Aminudin, Nurul Iman and Ahmad, Farediah and Bakhtiar, M. Taher and Mohamed Zulkifli, Razauden (2015) α-glucosidase and 15-lipoxygenase inhibitory activities of phytochemicals from calophyllum symingtonianum. Natural Products Communications, 10 (9). pp. 1585-1587. ISSN 1555-9475 (O), 1934-578X (P),

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Abstract

A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a positive result against 15-lipoxygenase inhibition.

Item Type:	Article (Journal)
Additional Information:	5209/44955
Uncontrolled Keywords:	α-Glucosidase, 15-Lipoxygenase, Calophyllum symingtonianum, Flavonoids, Coumarins.
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Depositing User:	Dr Muhammad Taher
Date Deposited:	07 Oct 2015 07:54
Last Modified:	25 Sep 2017 15:02
URI:	http://irep.iium.edu.my/id/eprint/44955

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