A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies

Wan Salim, Wan Wardatul Amani and Ding, Zhenweng and Ziaie, Babak (2008) A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies. In: 2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS), 21st-25 January 2007, Kobe, Japan.

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Abstract

In this paper, we report on an expandable height hydrogel stamper with built-in reservoir that can be used to repeatedly (without frequent re-inking) stamp functional biomolecules on planar and non-planar surfaces. We have successfully patterned fluorescein isothiocyante (FITC) labeled antibodies (antibodies for O-antigens of Bradyrhizobium japonicum made in rabbits) on planar (silicon) and nonplanar (SU8 on silicon with a height of ~ 70µm) topologies. The printed antibodies show the effectiveness of hydrogel stampers in delivering biomolecules on 3D topologies where the hydrogel could be adjusted to stamp on the sidewalls and bottom of deep trenches.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	7116/44332
Uncontrolled Keywords:	Hydrogel stamper, 3D topologies
Subjects:	T Technology > TA Engineering (General). Civil engineering (General) > TA164 Bioengineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering > Department of Biotechnology Engineering Kulliyyah of Engineering
Depositing User:	Dr Wan Wardatul Amani Wan Salim
Date Deposited:	11 Feb 2020 11:06
Last Modified:	11 Feb 2020 11:06
URI:	http://irep.iium.edu.my/id/eprint/44332

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