An adjustable force soft-contact lithography for patterning biomolecules on 3D topologies

Wan Salim, Wan Wardatul Amani and Humad, Shweta and Ayazi, Farrokh and Ziaie, Babak (2005) An adjustable force soft-contact lithography for patterning biomolecules on 3D topologies. In: 18th IEEE International Conference on Micro Electro Mechanical Systems, 2005. MEMS 2005., 30th January.-3rd February 2005, Miami, Florida.

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Abstract

In this paper, we report on a precision patterning technique using an adjustable-force soft-landing contact lithography that can be used to stamp functional biomolecules on planar and non-planar fragile surfaces. We have successfully patterned fluorescent antibodies (Alexa 568 antigoat IgG) on high frequency silicon microresonators with central vibrating bodies ranging from 20x10 to 480x240pm2 and arrays of 40pm diameter circular patterns with superior uniformity and without loss in proteins functionality. The printed antibodies were tested for effectiveness in binding fluorescent conjugated antigen (488 labeled goat anti-mouse IgG), and were shown to retain nearly-optimal bindings.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	7116/44331
Uncontrolled Keywords:	Hydrogel, pH-sensitive, microvalve, flow control, microfluidics, PDMS
Subjects:	Q Science > QD Chemistry T Technology > TK Electrical engineering. Electronics Nuclear engineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering > Department of Biotechnology Engineering Kulliyyah of Engineering
Depositing User:	Dr Wan Wardatul Amani Wan Salim
Date Deposited:	11 Feb 2020 10:21
Last Modified:	11 Feb 2020 10:21
URI:	http://irep.iium.edu.my/id/eprint/44331

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