Microelectrode design for particle trapping on bioanalysis platform

Ibrahim, S.Noorjannah and Alkaisi, Maan M. (2015) Microelectrode design for particle trapping on bioanalysis platform. Advanced Materials Research, 1115. pp. 543-548. ISSN 1022-6680

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Abstract

Microelectrode geometry has significant influence on particles trapping techniques used on bioanalysis platforms. In this paper, the particle trapping patterns of dipole, quadrupole and octupole microelectrode using dielectrophoretic force (DEP) are discussed. The microelectrodes were constructed on a metal-insulator-metal platform, built on a silicon nitride (Si3N4) coated silicon substrate. The back contact is made from 20 nm nickel-chromium (NiCr) and 100 nm gold (Au) as the first layer. Then, SU-8-2005 (negative photoresist) is used on the second layer to create microcavities for trapping the particles. The third layer, where the three geometries were patterned, is made from 20 nm NiCr and 100 nm Au layers. Prior to fabrication, the particles trapping patterns of the microelectrodes were profiled using a finite element software, COMSOL 3.5a. Trapping patterns for the three geometries were evaluated using polystyrene latex microbeads. Results from the experiment validate simulation studies in term of microelectrode trapping ability up to single particle efficiency. It provides the potential of converting the trapping platform into a lab-on-chip system.

Item Type:	Article (Journal)
Additional Information:	3823/41647
Uncontrolled Keywords:	microelectrode design; bio-analysis platform; particle trapping; Dielectrophoresis
Subjects:	T Technology > TA Engineering (General). Civil engineering (General) > TA164 Bioengineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering > Department of Electrical and Computer Engineering
Depositing User:	Siti Noorjannah Ibrahim
Date Deposited:	03 Aug 2015 15:15
Last Modified:	17 May 2016 16:53
URI:	http://irep.iium.edu.my/id/eprint/41647

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