Biochemical effects of Nigella sativa seeds in diabetic rats

Ahmed, Qamar Uddin (2006) Biochemical effects of Nigella sativa seeds in diabetic rats. Indian Journal of Experimental Biology , 44 (9). pp. 745-748. ISSN 0975-1009

PDF (Research article) - Published Version Restricted to Registered users only until 2020. Download (146kB) | Request a copy

Abstract

Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxidant enzymes like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase in liver and kidney. The results confirm the antidiabetic activity of N. sativa seeds extract and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats.

Item Type:	Article (Journal)
Additional Information:	4921/40985
Uncontrolled Keywords:	Antioxidants; Diabetes mellitus; Free radicals; Nigella sativa; Oxidative stress
Subjects:	Q Science > Q Science (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr Qamar Uddin Ahmed
Date Deposited:	04 Mar 2015 10:27
Last Modified:	04 Mar 2015 10:27
URI:	http://irep.iium.edu.my/id/eprint/40985

Actions (login required)

View Item