Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats

Herman, Hendy Putra and Darnis, Deny Susanti and Saad, Shahbudin and Bakhtiar, M. Taher and Ramli, Norazsida (2013) Wound healing properties of ethanolic extract of acrostichum aureum and acrostichum speciosum rhizome in rats. Journal of Tropical Resources and Sustainable Science, 1 (2). pp. 42-48. ISSN 2289-3946

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Abstract

This paper presents the assessment of wound healing properties of ethanolic extract of Acrostichum aureum and A. speciosum in rats. It was carried out on 6 treated groups with 6 rats each group. The excisional wound was made on the dorsal interscapular region of each rat by a 6 mm biopsy punch. T1 and T2 were treated with 5% and 10% A. aureum ethanolic extract in aqua cream, respectively. Meanwhile, T3 and T4 were treated with 5% and 10% A. speciosum ethanolic extract in aqua cream, respectively. Solcoseryl jelly and aqua cream were used as positive and negative controls. The treatments were applied topically twice daily, wound contraction and period of epithelization were measured every 2 days. The results showed that wound treated with 10% A. speciosum (T4) exerted faster wound contraction significantly (p < 0.05) compared to the negative control. It was also enhanced epithelization period (9.33 ± 3.20 days) of the wounds significantly (p < 0.05). In conclusion, these results strongly suggested the beneficial effects of both plant extracts for enhancing wound healing process.

Item Type:	Article (Journal)
Additional Information:	5641/36864
Uncontrolled Keywords:	Wound healing,Acrostichum aureum,Acrostichum speciosum,Excisional wound,Rats
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Biomedical Science
Depositing User:	Dr Muhammad Taher
Date Deposited:	09 Jun 2014 11:23
Last Modified:	20 Oct 2016 12:23
URI:	http://irep.iium.edu.my/id/eprint/36864

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