Microbial transformations of artemisinin – anti-malaria drug

Omar, Muhammad Nor and Khan, Naik T. and Hasali, Nor Hazwani and Moin, Syed Faraz and Alfarra, Helmi Yousif (2012) Microbial transformations of artemisinin – anti-malaria drug. Advances in Bioresearch, 3 (2). pp. 27-31. ISSN 0976 – 4585 (P), 2277-1573 (O)

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Abstract

In recent years, artemisinin (1) has remained an effective drug to treat malaria. Numerous approaches have been adapted to increase the efficacy of (1) against antibiotic resistant malarial parasite. Microbial biotransformation of (1) has been used recently to produce promising derivatives of (1) on a large scale with low costs. During the last decade several biotransformation studies on (1), by using microorganisms, have been reported. This literature review focuses on the most recent microbial transformation studies on artemisinin and its derivatives.

Item Type:	Article (Journal)
Additional Information:	5626/36505
Uncontrolled Keywords:	Artemisinin, Malaria, Biotransformation, Microorganisms, Hydroxylation
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Biotechnology
Depositing User:	Prof Dr Muhammad Nor Omar
Date Deposited:	05 May 2014 09:24
Last Modified:	05 May 2014 09:24
URI:	http://irep.iium.edu.my/id/eprint/36505

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