Haplophytin B from maclurodendron porteri

Bakhtiar, M. Taher and Darnis, Deny Susanti and Abd Hamid, Shafida and Edueng, Khadijah and Md. Jaffri, Juliana and Adina, Anugerah and Rezali, Mohd Fazlin (2014) Haplophytin B from maclurodendron porteri. Pakistan Journal of Pharmaceutical Sciences, 27 (1). pp. 179-181. ISSN 1011-601X

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Abstract

An alkaloid from Maclurodendron porteri has been isolated and characterized. Extraction process was conducted by acid-base extraction method followed by column chromatography. The structure was established by nuclear magnetic resonance spectroscopy and mass spectrometry. The compound was identified as haplophytin B which occurs commonly in the Rutaceae family. However, this is the first time this alkaloid was isolated and reported from the species. The compound showed no inhibition against Staphylococus aureus, Pseudomonas aeruginosa, Bacillus cereus and Escherichia coli and no cytotoxic activity against H199 and A549 cell lines.

Item Type:	Article (Journal)
Additional Information:	5209/32645
Uncontrolled Keywords:	Maclurodendron porteri, Rutaceae, furanoquinoline alkaloid, haplophytin B.
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Depositing User:	Dr Muhammad Taher
Date Deposited:	12 Nov 2013 14:39
Last Modified:	20 Jun 2018 16:27
URI:	http://irep.iium.edu.my/id/eprint/32645

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