Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis

Razak , Siti Shahrul Nazifah and Abdaziz, Siti Mutheerah and Radu, Son and Abas, Faridah and Neto, Viktor and Khatib, Alfi (2013) Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis. In: International Conference on Natural Products 2013 (ICNP 2013), 4-6 Mar 2013, Shah Alam.

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Abstract

Alternanthera sessilis is one of the herbal medicines used in Malaysia especially among Chinese race. The metabolite fingerprinting analysis of ethanolic extracts of leaves of A.sessilis was carried out using Fourier-transform infrared (FTIR) spectroscopy in combination with multivariate data analysis to differentiate between four different origins of plant harvested. Principle component analysis (PCA) of the infrared spectra showed an obvious cluster between origin 1(from Putrajaya) and origin 3 (from Rantau Panjang), meanwhile, origin 2 (from Serdang) and 4 (from Ampang) is almost closer by PC1 and PC2 (99.2% and 0.4% total variance, respectively) score plots. The results of PLS-DA similar with the PCA result. The samples were further analyzed using two-dimensional infrared correlation spectroscopy and the results showed remarkable differences between samples of different origins.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	6915/31368
Uncontrolled Keywords:	Alternanthera sessilis, FT-IR, 2D-IR, Multivariate data analysis, Metabolomics, multivariate data analysis
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr. Alfi Khatib
Date Deposited:	16 Dec 2013 12:36
Last Modified:	16 Dec 2013 12:36
URI:	http://irep.iium.edu.my/id/eprint/31368

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