Antimicrobial activity of Malaysian Donax grandis extracts

Mohd Daud, Jamaluddin and Hashim, Ridzwan and Taher, Muhammad and Mohd Hassan, Husna Hawa (2012) Antimicrobial activity of Malaysian Donax grandis extracts. Science Series Data Report, 4 (5). pp. 30-35. ISSN 1307-119X

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Abstract

The present investigation was carried out to evaluate the antibacterial activities of four different parts of Malaysian Donax grandis. Dried fruit, root, leaf and stem powder of D. grandis was successively extracted with hexane, dichloromethane and methanol using Soxhlet method. All extracts were screened for its antibacterial and antifungal activity using agar disc diffusion method. The microorganisms used for antibacterial and antifungal were, Staphylococcus aureus, Bacillus cereus, Psedomonas auraginosa, Escherichia coli, Candida albicans, Candida tropicalis and Candida krusei. Streptomycin (25 μg/disc) and Nystatine (30 μg/disc) was used as standards. The extracts (40 μg/disc) showed antimicrobial activity were subjected to minimum inhibitory concentration assay by two fold dilutions method. Hexane, dichloromethane and methanol extract exhibited in-vitro antimicrobial activity. None of the hexane and dichloromethane extracts showed antifungal activity.

Item Type:	Article (Journal)
Additional Information:	5678/26053
Uncontrolled Keywords:	Donax grandis, antimicrobial activity
Subjects:	Q Science > Q Science (General) Q Science > QR Microbiology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences Kulliyyah of Pharmacy Kulliyyah of Science > Department of Biotechnology
Depositing User:	Dr Jamaluddin Mohd Daud
Date Deposited:	30 Oct 2012 09:28
Last Modified:	22 Feb 2016 15:01
URI:	http://irep.iium.edu.my/id/eprint/26053

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