Efficacy and safety of viva QS capsule for nicotine addiction in Malaysian adult smokers

Mohamad Noor, Zaswiza and Nik Mohamed, Mohamad Haniki and Md Aris, Mohd Aznan and Draman, Samsul and Shaikh Rahman Bux, Siti Halimah Bux (2010) Efficacy and safety of viva QS capsule for nicotine addiction in Malaysian adult smokers. In: IIUM Research, Innovation & Invention Exhibition (IRIIE 2010), 26 - 27 January 2010, Kuala Lumpur.

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Abstract

We conducted a randomised, double-blind, placebo-controlled study to evaluate the effectiveness of Viva QS® capsule, a supplement consisting of twelve herbs, for the management of nicotine addiction. Smokers meeting study criteria were recruited into the study. Follow-up was undertaken for 6 months, with three assessment time points for smoking status andwithdrawal symptoms. Brief counseling was provided at each follow-up via telephone call at week 4 and 12. At week 24, face-to-face follow-up was done and self-reported abstinence was validated by measuring expired carbon monoxide level and cotinine in urine and/or saliva samples. Result: Of 155 smokers recruited, mean age was 35.2 ± 8.36 years. Mean baseline Fagerström test for nicotine dependence (FTND) score was 5.03 ± 1.39. 7-days point prevalence quit rate was 22.4% at week 24 [Viva QS = 30.7% vs. placebo = 13.9%]; p = 0.015; OR = 2.74 (CI =1.197-6.282), 34.7% at week 12 [42.7% vs. 26.2%; p = 0.038, OR = 2.08 (CI = 1.04-4.16) and 24.5% at week 12 [32% vs. 16.7%]; p =0.031; OR = 2.35 (CI = 1.07-5.17). Most common adverse events reported were sore throat (Viva QS =28.8% vs. placebo = 36.6%), dry mouth (17.8% vs. 16.9%) and cough (11% vs. 8.4%) There were no significant differences in all adverse events reported by subjects in both groups. Conclusion: Viva QS ® at least doubled smoking cessation rate vs. placebo in smokers with moderate to high level ofnicotine dependence without any significant adverse effects.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	5494/22330
Uncontrolled Keywords:	viva QS capsule
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User:	DR ZASWIZA BINTI MOHAMAD NOOR
Date Deposited:	18 Jul 2013 09:37
Last Modified:	18 Jul 2013 09:37
URI:	http://irep.iium.edu.my/id/eprint/22330

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