Time-resolved metabolomics of Murrah buffalo milk yoghurt reveals fermentation- and storage-dependent metabolite dynamics with insights into bioactive potential

Mansor, Muzammeer and Kit, Tan Jen and Al-Obaidi, Jameel R. and Selamat, Jinap and Abdull Razis, Ahmad Faizal and Khatib, Alfi and Jambari, Nuzul Noorahya (2026) Time-resolved metabolomics of Murrah buffalo milk yoghurt reveals fermentation- and storage-dependent metabolite dynamics with insights into bioactive potential. Food Chemistry, 506 (NA). pp. 1-15. ISSN 0308-8146 E-ISSN 1873-7072

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Abstract

This study applied LC-MS/MS-based metabolomics to profile biochemical changes during fermentation and storage. A total of 173 metabolies were annotated, with 172 showing significant differential expression, mainly organic acids, fatty acids, alkaloids, nucleic acids, and carbohydrates. PLS-DA revealed distinct temporal clustering, driven by 88 key metabolites (VIP >1).

Item Type:	Article (Journal)
Additional Information:	Alfi Khatib is the first IIUM author
Uncontrolled Keywords:	Buffalo milk; Yoghurt; Cold storage; Metabolomic; LC–MS/MS
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr. Alfi Khatib
Date Deposited:	22 Sep 2026 13:06
Last Update:	22 Sep 2026 13:06
Queue Number:	2026-09-Q5177
URI:	http://irep.iium.edu.my/id/eprint/131375
Indexed In:	WOS and SCOPUS, Google Scholar

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