Evolution and assessment of biomarkers in perioperative and critical care medicine

Md Ralib, Azrina and Aidid, Afif Hakimi and Mohd Nor, Mohd Amiruddin and Aziz, Ahmad Akmal and Soo, Ki Yang (2021) Evolution and assessment of biomarkers in perioperative and critical care medicine. In: MSA Year Book 2020/2021. MSA Year Book (2020/2021). Malaysian Society of Anaesthesiologists, Kuala Lumpur, Malaysia, pp. 31-40.

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Abstract

explains how biomarkers are evolving from simple lab tests to multidimensional tools for risk prediction and organ‑specific monitoring in perioperative and ICU patients. They now support diagnosis, risk stratification, early detection of organ injury, and treatment guidance, especially in cardiovascular risk, kidney injury, and sepsis.​ No single biomarker is sufficient; combinations interpreted with clinical data and newer analytic methods (ROC, reclassification, machine learning) are needed to add real value. The main challenge is proving that biomarker‑guided strategies actually change management and improve outcomes.

Item Type:	Book Chapter
Additional Information:	MSA Year Book ISSN: 2462-1307
Uncontrolled Keywords:	biomarkers
Subjects:	R Medicine > RC Internal medicine > RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Anaesthesiology & Intensive Care Sultan Ahmad Shah Medical Centre (SASMEC)
Depositing User:	Dr AFIF HAKIMI AIDID
Date Deposited:	26 Dec 2025 15:41
Last Modified:	26 Dec 2025 15:41
Queue Number:	2025-12-Q1243
URI:	http://irep.iium.edu.my/id/eprint/126332

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