Adult moyamoya syndrome as a manifestation of varicella-associated cerebral vasculopathy: a case report

Rozi, Nur Raziana and Bahtiar, Mohamad Syahiirul Afifi and Hassan, Radhiana and Basiam, Sulaila (2023) Adult moyamoya syndrome as a manifestation of varicella-associated cerebral vasculopathy: a case report. IIUM Medical Journal Malaysia, 22 (3). pp. 162-165. ISSN 1823-4631 E-ISSN 2735-2285

	PDF - Published Version Restricted to Registered users only Download (1MB) | Request a copy
	PDF - Supplemental Material Download (149kB)

Abstract

Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by progressive large intracranial artery narrowing and development of small vessel collaterals. Moyamoya syndrome (MMS) refers to the angiographic findings of MMD with predisposing medical conditions. Varicella-associated cerebral vasculopathy (VACV) is a severe complication of varicella zoster virus (VZV) infection and its association with MMS is rare in adult. We report on a case of a 55-year-old lady who presented with progressively worsening dysphasia and left lower limb weakness following a week of right herpes zoster ophthalmicus infection. The initial Magnetic Resonance Imaging (MRI) of brain demonstrated features of encephalitis with micro abscesses. Her serial repeated MRI brain imagings subsequently demonstrated worsening of cerebral infarctions with right internal carotid artery stenosis and basal ganglia collaterals suggestive of Moyamoya vasculopathy. This case highlights the rare association of VACV with MMS and should be considered as a potential serious complication in patients with VZV infection

Item Type:	Article (Case Report)
Uncontrolled Keywords:	Hemiparesis, Moyamoya syndrome, Varicella zoster
Subjects:	R Medicine > RC Internal medicine R Medicine > RC Internal medicine > RC321 Neuroscience. Biological psychiatry. Neuropsychiatry R Medicine > RC Internal medicine > RC66 Clinical cases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Sultan Ahmad Shah Medical Centre (SASMEC)
Depositing User:	Dr Nur Raziana Binti Rozi
Date Deposited:	09 Oct 2025 14:39
Last Modified:	09 Oct 2025 14:51
URI:	http://irep.iium.edu.my/id/eprint/123611

Actions (login required)

View Item