Biosimilars: mechanisms of action, clinical efficacy and therapeutic implications

Sadikan, Muhammad Zulfiqah and Ahmad Hairi, Haryati and Mohmad Sabere, Awis Sukarni (2024) Biosimilars: mechanisms of action, clinical efficacy and therapeutic implications. In: Compilation of Research Papers on Stem, June 2024 (Science, Technology, Engineering & Mathematics). MNNF Publisher, Senawang, Malaysia, pp. 43-48.

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Abstract

Biosimilars have been defined as agents used to deliver biopharmaceuticals that are chemically, functionally, and therapeutically equivalent to approved reference biologics. These biological agents are derived from living organisms or cells, and comparability tests are carried out to assess whether they can function in the same way as the corresponding reference products. The future of healthcare as a result of biologic-based therapies has a high potential for transforming health systems, making them more accessible and affordable. Therefore, biosimilars as a part of the improved healthcare delivery systems will be extremely beneficial in the future. In the current chapter, the author delves into how biosimilars work and other aspects that distinguish them from reference products. It also assesses biosimilar safety and efficacy in real-world clinical situations by comparing therapeutic properties to the initial reference biologic. Furthermore, this chapter analyses the potential protective benefits and risks of biosimilars upon systematic application, presenting a concise viewpoint for current and future healthcare advancements. By considering these issues, this chapter covers different aspects of biosimilars' impact on both patients and healthcare systems.

Item Type:	Book Chapter
Uncontrolled Keywords:	Biosimilars, mechanisms of action, clinical efficacy, therapeutic implications, patient perspectives
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy
Depositing User:	Dr Awis Sukarni Mohmad Sabere
Date Deposited:	21 Jan 2025 12:46
Last Modified:	22 Jan 2025 14:41
URI:	http://irep.iium.edu.my/id/eprint/118311

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