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Navigating iron deficiency anaemia in pre-menopausal women: beyond nutritional and menstrual paradigms

Abd Rahman, Mohd Aizuddin and Sulaiman, Nur Suriati and Sulaiman, Ahmad Fardi (2024) Navigating iron deficiency anaemia in pre-menopausal women: beyond nutritional and menstrual paradigms. Medicine and Health, 19 (5). p. 76. E-ISSN 2289-5728

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Abstract

Introduction: Iron deficiency anaemia (IDA) is a common condition that affects a significant number of premenopausal women globally. There are various factors that can contribute to this condition, such as menstruation, pregnancy, insufficient iron intake, malabsorption, intravascular haemolysis, and gastrointestinal blood loss. Premenopausal women often attribute it to menstrual blood loss. As a result, referrals for gastrointestinal evaluations of premenopausal women are rare. Case report: A 45-year-old woman presented to the primary care clinic with worsening lethargy and a reduced appetite for two months. She has an underlying iron deficiency anaemia on regular haematinics and is under primary care follow-up. The haemoglobin level ranges from 8.5 to 11.5 g/dl. She underwent two admissions for symptomatic anaemia, each time receiving a blood transfusion. There is no palpitation, shortness of breath, rectal bleeding, altered bowel habits, or constipation. She also has no family history of malignancy. Her menses were regular, and she follows a high-iron diet. Fecal stool-occult blood was negative. Her worsening symptoms prompted a referral for a colonoscopy due to an unexplained IDA, potentially indicating colon cancer. Colonoscopy showed a splenic flexure tumor, and HPE revealed splenic flexure adenocarcinoma. She then underwent a laparoscopic left hemicolectomy. Conclusion: When dealing with unexplained IDA, one should apply a high index of suspicion, and malignancy is likely one of the main causes, especially in pre-menopausal age.

Item Type: Article (Abstract)
Uncontrolled Keywords: Anaemia; iron deficiency; pre-menopausal; colorectal cancer
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA644.3 Chronic and Noninfectious Diseases and Public Health
R Medicine > RD Surgery
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011)
Depositing User: DR MOHD AIZUDDIN ABD RAHMAN
Date Deposited: 09 Oct 2024 09:06
Last Modified: 09 Oct 2024 10:00
URI: http://irep.iium.edu.my/id/eprint/114909

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