Dietary supplementation of Polygonum chinense improves the immunity of Asian seabass, Lates calcarifer (Bloch, 1790) against Vibrio harveyi infection

Abdul Razak, Rashidah and Shariff, Mohamed and Md. Yusoff, Fatimah and Ismail, Intan Safinar (2023) Dietary supplementation of Polygonum chinense improves the immunity of Asian seabass, Lates calcarifer (Bloch, 1790) against Vibrio harveyi infection. Fish and Shellfish Immunology Reports, 5. pp. 1-17. ISSN 26670119

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Abstract

Aquaculture plays a significant role in the overall fish production in Malaysia, contributing a substantial quantity of food-fish amounting to roughly 573,683 tonnes with an estimated economic value of US$860 million in 2022. However, diseases have become a significant limitation for aquaculture production. Therefore, herbal immu-nostimulant has been considered a natural and practical approach of preventing disease infection in fish. The ability of Polygonum chinense extract (PCE) on haemato-biochemistry parameters, immunomodulatory properties, and disease resistance of Lates calcarifer (Asian seabass) under Vibrio harveyi challenge was evaluated in this study, with a focus on dose-response associations and variability over various exposure durations (0-, 7- and 14- day post-infection). A total of 480 Asian seabass (9.5 ± 0.2 g) were distributed in 12 aquaria and fed four diets supplemented with 0 (control), 2, 5 and 10 g/kg diet for 60 days before being challenged with V. harveyi. Dietary PCE significantly improved (P < 0.05) survival, with the dose of 10 g/kg showing the highest survival rate (90 %) when compared to the control (60 %). Additionally, hematological (red and white blood cell counts, hemoglo- bulin, packed cell volume, and mean corpuscular volume) and immunological (activities of lysozyme, phagocytic activity and respiratory burst, and serum total immunoglobulin) properties were significantly increased (P <0.05) in comparison to the control group. In contrast, serum aspartate aminotransferase and alanine amino-transferase levels, as well as glucose level were significantly reduced (P < 0.05) in PCE-fed fish compared to the control group. Conclusively, the current study discovered that supplementing fish feed with P. chinense extract improves fish haemato-biochemical profile, immunocompetence and disease resistance to V. harveyi infection.

Item Type:	Article (Journal)
Additional Information:	108279/9090
Uncontrolled Keywords:	Lates calcarifer, vibrio harveyi, polygonum chinense, haemato-biochemical, immune response, disease resistance
Subjects:	S Agriculture > SH Aquaculture. Fisheries. Angling > SH151 Aquaculture - Fish Culture S Agriculture > SH Aquaculture. Fisheries. Angling > SH370 Fisheries - Shellfish fisheries-Shellfish Culture
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science Kulliyyah of Science > Department of Marine Science
Depositing User:	Mr Mohamad Ridzuan Musa
Date Deposited:	21 Nov 2023 13:28
Last Modified:	22 Nov 2023 09:09
URI:	http://irep.iium.edu.my/id/eprint/108279

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