Concentrated growth factor as an alternative membrane material in periodontal regeneration: a case report

Mohd Noh, Nur Zety and Salehuddin, Nurul Qamar and Ali, Sharul Nisha and Mohamad, Ikhwan Hakimi and Ariffin, Farha (2023) Concentrated growth factor as an alternative membrane material in periodontal regeneration: a case report. IIUM Journal of Orofacial and Health Sciences, 4 (1). pp. 80-88. E-ISSN 2735-0584

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Abstract

The risk of further periodontal breakdown increases with a deep intrabony defect. Non-surgical periodontal therapy could pose a challenge and surgical intervention is mainly required to manage the defect. Autologous platelet concentrates such as concentrated growth factor (CGF) may improve surgical outcome due to its enrichment with growth factors. Nevertheless, the outcomes of using CGF as a biomaterial in periodontal regenerative therapy is inconclusive. This case report describes the regenerative management of an intrabony defect on all the first molars of a 24-year-old Malay lady diagnosed with Generalised Periodontitis, Stage III, Grade C. A guided tissue regeneration strategy was utilised on all the first molars except on tooth 46, which was treated with xenografts and a biologic adjunct of CGF. Patient was recalled regularly every week up to two months following the procedure, followed by a three-month interval review. The results showed promising outcomes with an average of 4 mm probing pocket depth reduction and 79.1% radiographic bone fill for both regenerative strategies. The utilisation of biologic adjuncts such as CGF, could offer a viable alternative to collagen membrane in periodontal regeneration without compromising clinical results.

Item Type:	Article (Case Report)
Uncontrolled Keywords:	Concentrated Growth Factor, guided tissue regeneration, membrane, periodontitis, xenograft
Subjects:	R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Restorative Dentistry
Depositing User:	NUR ZETY MOHD NOH
Date Deposited:	17 Apr 2023 10:41
Last Modified:	17 Apr 2023 10:41
URI:	http://irep.iium.edu.my/id/eprint/104434

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